Brian Smith received his B.S. in chemistry from Grand Valley State University, Allendale, MI, where he studied the mechanism of beta-lactamase enzymes in the laboratory of Dr. David Leonard. He received his Ph.D. degree in biochemistry from The Ohio State University in Columbus, OH, working with Dr. Jane Jackman to investigate the catalytic mechanism of the eukaryotic tRNA(His) guanylyltransferase (Thg1) enzyme. Following his graduate studies, he worked as a post-doctoral fellow in the laboratory of Dr. Gloria Culver at the University of Rochester in Rochester, NY where he studied alternative pathways of ribosome biogenesis and rRNA processing in bacteria. Brian then joined the faculty at LTU in 2018 as an assistant professor in the Department of Natural Sciences where he teaches general chemistry, organic and biochemistry courses. His current research is focused on understanding the catalytic mechanisms of enzymes that are responsible for antibiotic resistance in bacteria.
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