Title of Project: Antibiotic Elution from PMMA Bone Cement
Type: Research
Guide: Nicole Villeneuve
Daptomycin and Tobramycin are antibiotics mixed into PMMA bone cement to kill bone infections. In this Quest project Tyson DeLandsheer is studying the amount of the antibiotics that elute from the bone cement over time, and whether these two different antibiotics effect elution levels. High Performance Liquid Chromatography will be used to find the amounts of antibiotic that are eluted form each bone cement sample. This information will be processed to find any trends between the different initial values of the antibiotics. The same experiments will be run under strain. This will more accurately represent a joint.